Clinical Trial

Colon-delivered Riboflavin and Gut Microbiota Composition

Study acronym: CONCOL
Recruiting
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Summary
Recent studies suggest B-vitamins such as riboflavin to possess prebiotic-like effects. However, there is still a lack of understanding of the exact host health benefits vs. conventional systemically available vitamin forms. The present study explores the benefit of colon-delivered vitamin B2 vs. conventional vitamin B2 in comparison to placebo in an aging population on gut microbiota and metabolic activity as well as gut health.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-07-22; most recent amendment 2026-03-17.
Trial Details
NCT Number NCT07093463
Lead Sponsor dsm-firmenich Switzerland AG
Collaborators: Analyze & Realize
Conditions Microbiome Dysbiosis, Gut Health
Enrollment 90 participants
Start Date 2025-07-18
Primary Completion 2026-08 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-03-19