Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries

Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient. Lung protective ventilation provides breathing at a set volume determined by patient ideal body weight, along with a set rate to maintain adequate breathing. The pressures in the lower airway are kept less than 30 cm of H20 while a pressure of 5cm of H20 is applied to prevent lung collapse. Recently to above mentioned regimen a driving pressure is added which is a difference between lower airway pressure and pressure applied to prevent lung collapse. Ventilatory settings are adjusted to keep this driving pressure less than 15 cm of H2O.

NCT Number	NCT07092943
Lead Sponsor	Rawalpindi Medical College
Conditions	Mechanical Ventilation, Lung Protective Ventilation, Driving Pressure
Enrollment	70 participants
Start Date	2025-07-20
Primary Completion	2025-10-20 (estimated)
Study Completion	2025-10-20 (estimated)
Updated on ClinicalTrials.gov	2025-07-30