Clinical Trial

Preeclampsia and Fetal Heart Malformations: Looking to Maternal Heart

Study acronym: MAMAH
Recruiting
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Summary
The goal of this study is to describe the maternal hemodynamic parameters detected by UltraSonic Cardiac Output Monitor (USCOM®) in women carrying a fetus with a congenital heart disease (CHD) and to possibly describe an association between those parameters and the presence of a fetal cardiac anomaly. It will also learn about: * the number of cases of preeclampsia in our population of women carrying fetuses with CHD * the relationship between maternal hemodynamic profile and maternal and perinatal outcome * the associations between maternal hemodynamic parameters and the specific heart defect subtype * the relationship between maternal hemodynamic parameters and fetal cardiac parameters in our population. The haemodynamic evaluation will be performed at the time of diagnosis of CHD and then every two weeks until delivery. A further evaluation will be performed immediately after delivery (within 72 hours).
Trial Details
NCT Number NCT07092644
Lead Sponsor Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions Congenital Heart Disease
Enrollment 108 participants
Start Date 2023-11-16
Primary Completion 2026-11 (estimated)
Study Completion 2026-11 (estimated)
Updated on ClinicalTrials.gov 2025-07-30