Clinical Trial

Hemodynamic Effects of a Standardized Grape Seed Extract Supplementation

Study acronym: ZENITH
Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of this study is to evaluate whether a standardized grape seed extract, compared to placebo, can significantly influence systolic blood pressure (SBP) in individuals with high-normal blood pressure (BP) who are adhering to a low-sodium Mediterranean diet. Additionally, the effects of the grape seed extract on diastolic blood pressure (DBP), other hemodynamic parameters, and the Perceived Stress Score will be assessed.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-07-24; most recent amendment 2026-04-17.
Status change: Not Yet Recruiting → Recruiting 2026-04-17
Trial Details
NCT Number NCT07090876
Lead Sponsor Indena S.p.A
Conditions High-normal Blood Pressure
Enrollment 60 participants
Start Date 2026-04-10
Primary Completion 2027-01-30 (estimated)
Study Completion 2027-01-30 (estimated)
Updated on ClinicalTrials.gov 2026-04-22