PRF vs. Graftless Sinus Lift With Implant Placement

The goal of this clinical trial is to evaluate the effectiveness of sinus floor elevation using platelet-rich fibrin (PRF) compared to a graftless approach in adult patients with atrophic posterior maxilla (residual bone height 5-7 mm) requiring dental implant rehabilitation. The main questions it aims to answer are: Does PRF enhance bone height gain more effectively than graftless sinus elevation? Does PRF improve implant stability and reduce marginal bone loss compared to the graftless approach? Researchers will compare the outcomes of PRF-grafted implants versus non-grafted implants to see if PRF improves radiographic and clinical results in single-stage implant placement. Participants will: Undergo internal sinus lift via crestal drilling approach Be randomly assigned to one of two groups: Group I: sinus lift without graft material Group II: sinus lift with PRF as the sole grafting material Receive simultaneous dental implant placement during the sinus lift Be monitored through clinical exams and radiographic imaging over 6 months postoperatively

NCT Number	NCT07090694
Lead Sponsor	Dar Al Uloom University
Conditions	Maxillary Sinus Floor Augmentation, Alveolar Bone Loss, Atrophy, Platelet-rich Fibrin, Dental Implant
Enrollment	8 participants
Start Date	2025-02-01
Primary Completion	2025-08 (estimated)
Study Completion	2025-08 (estimated)
Updated on ClinicalTrials.gov	2025-07-29