Clinical Trial

Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.

Study acronym: Tomo-BPCO
Recruiting
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Summary
Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD. It is supposed to be symmetrical between the 2 lungs with the same PEEPi. EIT can measure the distribution of tidal ventilation and interlung lung insufflation delay on the impedance time curve of each lung. Moreover, it is possible in intubated COPD patients to assess one lung PEEPi during low flow insufflation with pressure-EIT monitoring. This study aims to measure interlungs insufflation delay under mechanical ventilation in COPD patients
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-07-21; most recent amendment 2026-05-28.
Status change: Not Yet Recruiting → Recruiting 2025-09-01
Trial Details
NCT Number NCT07090460
Lead Sponsor Centre Hospitalier de la côte Basque
Conditions Acute Respiratory Distress Syndrome (ARDS)
Enrollment 30 participants
Start Date 2025-11-22
Primary Completion 2026-08 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-06-01