Clinical Trial

Exploring Biological Markers of Driver Fatigue for Enhanced Road Safety

Study acronym: FATIGUE
Completed
View on ClinicalTrials.gov →
Summary
The aim of this study is to assess the effectiveness of biological markers in detecting fatigue/sleepiness in a sample of the general driving population in Belgium. The link between the collected biomarkers (oral fluid sample), observed signs of sleepiness in the driver and self-reported driver variables will be analysed. The analysis of the biological samples aims to measure endogenous metabolite levels that are possibly indicative for sleepiness of the donor driver. The respective metabolites will be chosen based on the results of a preceding clinical study (https://clinicaltrials.gov/study/NCT05585515). The objective of this study is to verify and validate the proposed metabolites as biomarkers for driver sleepiness in road traffic.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-07-20.
Status change: Recruiting → Completed 2026-03-20
Trial Details
NCT Number NCT07089342
Lead Sponsor University of Zurich
Collaborators: Vias Institute Brussel, Nationaal Instituut voor Criminalistiek en Criminologie Brussel
Conditions Drowsiness, Sleepiness, Fatigue
Enrollment 511 participants
Start Date 2025-08-29
Primary Completion 2025-12-19 (estimated)
Study Completion 2025-12-19 (estimated)
Updated on ClinicalTrials.gov 2026-03-25