Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback

This single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke. The study will include 15 individuals who have experienced a stroke and 15 healthy adults, each aged 20 years or older. Participants will walk on both tied-belt and split-belt treadmills under various training conditions, including backward-directed resistance (applied at the pelvis, ankle, or both) and real-time sensory feedback (visual, auditory, or combined). These interventions will be applied individually and in combination to identify the most effective environment for promoting symmetrical gait patterns. Each session will last approximately two hours. The equipment used is non-invasive, and the risk to participants is minimal.

NCT Number	NCT07087769
Lead Sponsor	The University of Texas Medical Branch, Galveston
Conditions	Stroke, Split-belt Treadmill, Resistance Exercise, Feedback, Gait Training
Enrollment	30 participants
Start Date	2025-07-25
Primary Completion	2026-12-01 (estimated)
Study Completion	2026-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-01