Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors

This is a study that will enroll patients with cancer who have tumors that may have spread. The patients will know what medication they are being given. There will be 2 parts to the study. For the first part of the study only one medication will be taken, and the dose changed to a higher dose over time. In the second part of the study tow medications will be taken and the dose of the medication may be changed to a higher dose.

NCT Number	NCT07086768
Lead Sponsor	Lei Zheng Collaborators: Biosin USA, Inc.
Conditions	Solid Tumor, Advanced Solid Tumor, Metastatic Solid Tumor
Enrollment	57 participants
Start Date	2026-01-26
Primary Completion	2027-08-07 (estimated)
Study Completion	2028-08-07 (estimated)
Updated on ClinicalTrials.gov	2026-06-03