Clinical Trial

Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children

Study acronym: ASCOT
Recruiting
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Summary
OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome) in children is a frequent respiratory disorder, whose prevalence is estimated at between 1.2 and 5.7%, and which, if left untreated, can cause severe medical complications. This prevalence tends to be underestimated. Diagnosis is made following a clinical examination noting the presence of characteristic clinical and polysomnographic criteria. Multidisciplinary management has been widely described in the literature, and various therapeutic options have been indicated. Rapid maxillary expansion has proved highly effective in the treatment of this condition. This syndrome is a real public health problem and must be diagnosed as early as possible. Through our research, we would like to study whether there is a causal link between an orthodontic problem of the transverse direction and the presence of SAHOS in children. In other words, we would like to assess whether children who clinically present an orthodontic deficiency of their transverse dimension are more likely to develop SAHOS than children without this deficit. If this proves to be true, then a new clinical sign could enable certain healthcare professionals to detect this syndrome early, and be able to refer patients to physicians as soon as possible.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-07-18.
Status change: Not Yet Recruiting → Recruiting 2026-03-27
Trial Details
NCT Number NCT07086612
Lead Sponsor Fondation Hôpital Saint-Joseph
Conditions Obstructive Sleep Apnea, Transverse Maxillary Deficiency
Enrollment 102 participants
Start Date 2025-11-06
Primary Completion 2026-09-01 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-30