Clinical Trial

Effect of Different Positive End-Expiratory Pressure (PEEP) Levels on Optic Nerve Sheath Diameter

Completed
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Summary
The goal of this prospective observational study is to evaluate the effects of different PEEP values on the optic nerve sheath diameter (ONSD), a noninvasive indicator of intracranial pressure (ICP), in patients undergoing vertebral surgery. The main question it aims to answer is how mechanical ventilation setting of 5 and 10 cmH2O PEEP effect optic nerve sheath diameter after surgery at extubation.
Trial Details
NCT Number NCT07085949
Lead Sponsor Izmir City Hospital
Conditions Optic Nerve Sheath Diameter
Enrollment 105 participants
Start Date 2025-07-30
Primary Completion 2026-01-01 (estimated)
Study Completion 2026-01-02 (estimated)
Updated on ClinicalTrials.gov 2026-02-24