Clinical Trial

Effect of Different Positive End-Expiratory Pressure (PEEP) Levels on Optic Nerve Sheath Diameter

Completed
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Summary
The goal of this prospective observational study is to evaluate the effects of different PEEP values on the optic nerve sheath diameter (ONSD), a noninvasive indicator of intracranial pressure (ICP), in patients undergoing vertebral surgery. The main question it aims to answer is how mechanical ventilation setting of 5 and 10 cmH2O PEEP effect optic nerve sheath diameter after surgery at extubation.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-07-17.
Status change: Not Yet Recruiting → Completed 2026-02-23
Trial Details
NCT Number NCT07085949
Lead Sponsor Izmir City Hospital
Conditions Optic Nerve Sheath Diameter
Enrollment 105 participants
Start Date 2025-07-30
Primary Completion 2026-01-01 (estimated)
Study Completion 2026-01-02 (estimated)
Updated on ClinicalTrials.gov 2026-02-24