Perfusion Related Evaluation of Systemic and Renal Vulnerability to Events in CABG

The goal of this observational study is to learn whether high abdominal pressure or low blood flow pressure to the kidneys is linked to kidney injury after heart surgery. The main questions it aims to answer are: Does high abdominal pressure increase the risk of kidney injury after cardiac surgery? Can low blood flow pressure to the kidneys help predict who may develop kidney problems? Participants in this study are adults undergoing heart surgery, such as coronary artery bypass grafting (CABG) or valve surgery. Researchers will measure abdominal pressure and blood pressure continuously before and after surgery using medical devices that are already part of routine care. This study does not involve any changes to standard treatment. Participants will: Have their abdominal and blood pressures continuously monitored using existing devices Have blood and urine tests to check kidney function Be followed during their hospital stay and up to 30 days after surgery to assess outcomes like length of stay, readmission, and survival This study takes place at two hospitals-one in Poland and one in the United States. Researchers hope the findings will help identify early warning signs of kidney injury and improve monitoring practices after heart surgery.

NCT Number	NCT07085286
Lead Sponsor	Medical University of Lublin Collaborators: Wake Forest University Health Sciences
Conditions	AKI - Acute Kidney Injury, CABG
Enrollment	45 participants
Start Date	2026-01-01
Primary Completion	2026-07-01 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-07-25