Clinical Trial

Evaluation of Tretinoin Cream on the Integrity of Aged Forearm Skin

Completed Phase 2/3
View on ClinicalTrials.gov →
Summary
The purpose of this research is to determine whether once nightly application of tretinoin 0.1% cream to forearm skin reduces the frequency of skin tears and bruising (solar purpura), and changes skin thickness over a period of 6 months.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-07-16.
Status change: Enrolling by Invitation → Completed 2026-05-23
Trial Details
NCT Number NCT07084116
Lead Sponsor James Thomas Pathoulas
Conditions Skin Tear, Solar Purpura, Dermatoporosis
Enrollment 15 participants
Start Date 2025-07-14
Primary Completion 2026-05-23 (estimated)
Study Completion 2026-05-24 (estimated)
Updated on ClinicalTrials.gov 2026-05-28