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Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait

StatusRecruiting
PhaseNot specified
Started
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Record status
This record was last updated July 24, 2025 (before its estimated August 23, 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
This is a cross-sectional, clinical research study comparing postmenopausal women of African Descent (AD) with different hemoglobin genotypes: normal and sickle cell trait (SCT). This research study has two purposes. The first purpose is to determine whether having SCT is a risk factor for the development of bone thinning in older women. The second purpose is to investigate whether women with SCT have reduced muscle function and increased frailty compared to women without SCT. The investigators estimate enrolling 50 female volunteers who are at least 50 years old and have not had a menstrual period for at least 12 consecutive months. Volunteers need not know whether they have SCT as this will be evaluated as part of the study.
Trial Details
NCT Number NCT07083531
Lead Sponsor UConn Health
Conditions
(from sponsor)		 Sickle Cell Disease, Sickle Cell Trait
Related terms Anemia, Sickle Cell, Sickle Cell Trait
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov