Clinical Trial

JOCOAT Safety and Tolerability Clinical Trial GLAD-04

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Summary
This study will assess the safety and efficacy of a new liquid anti-adhesion device, JOCOAT(TM) APN-3003 in patients undergoing knee anterior cruciate ligament reconstruction (ACLR) surgery. This is a single-center, prospective study. Safety and clinical outcomes will be compared with historical controls from enrolled study site patients from NCT03935750 (STABILITY 2) which has evaluated outcomes following ACL rupture in young athletes. A maximum of 24 patients aged 15-25 years undergoing primary anatomic ACLR with quadriceps tendon (QT) graft following a standardized surgical treatment algorithm will be enrolled. All patients will receive JOCOAT(TM) APN-3003 at the end of their surgery.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-07-21.
Trial Details
NCT Number NCT07081815
Lead Sponsor ARC Medical Inc.
Conditions Surgical Adhesions
Enrollment 24 participants
Start Date 2025-09
Primary Completion 2026-08 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2025-09-02