Percutaneous Intercostal Cryoneuromodulation Onset Timing.

Percutaneous Intercostal Cryoneurolysis is a promising technique that addresses acute postoperative pain after Nuss procedure for pectus excavatum. However its onset timing has not yet been determined. A physical examination would assess the variation of chest skin sensitivity to soft touch, cold (water at 4°C), and heat (water at 40°C) through days following the cryoneurolysis procedure.

NCT Number	NCT07081620
Lead Sponsor	Papa Giovanni XXIII Hospital
Conditions	Cryotherapy Effect, Pectus Excavatum
Enrollment	20 participants
Start Date	2025-06-07
Primary Completion	2026-09 (estimated)
Study Completion	2026-11 (estimated)
Updated on ClinicalTrials.gov	2025-07-23