Clinical Trial

Oklahoma Study of Native American Pain Risk IV: Smoking Cessation and Pain

Study acronym: OK-SNAPIV
Recruiting
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Summary
The goal of this pilot study is to assess whether 4-weeks of verified smoking abstinence following financial incentive treatment for smoking cessation improves physiological markers of chronic pain risk in adult Native American smokers. The main aims to answer are: 1. Determine study feasibility. 2. Obtain effect sizes for changes in pain amplification and pain inhibition in abstinent vs non-abstinent Native Americans. 3. Obtain effect sizes for variables in the conceptual model of the Native American smoking-pain relationship.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-07-14.
Status change: Not Yet Recruiting → Recruiting 2026-02-26
Trial Details
NCT Number NCT07080788
Lead Sponsor University of Oklahoma
Conditions Smoking Cessation Intervention, Pain, Smoking (Tobacco) Addiction
Enrollment 150 participants
Start Date 2025-09-01
Primary Completion 2027-06 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-03-02