A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension

This study is a prospective, single-center, randomized controlled trial focusing on patients with acute necrotizing pancreatitis (ANP) complicated by pancreatic sinistral portal hypertension (PSPH). The study aims to study the impact of total splenectomy on the debridement efficacy, perioperative recovery, and prognosis of patients with ANP complicated by PSPH.

NCT Number	NCT07080697
Lead Sponsor	Zhejiang University
Conditions	Acute Necrotizing Pancreatitis, Portal Hypertension
Enrollment	66 participants
Start Date	2025-07-30
Primary Completion	2027-02-28 (estimated)
Study Completion	2028-02-29 (estimated)
Updated on ClinicalTrials.gov	2025-07-23