Sepsis and Myocarditis

This prospective cohort study aims to investigate the cardiac manifestations of sepsis and their influence on disease outcomes among adult patients at Jimma University Medical Center, Ethiopia, from May 2025 to May 2026. The research will include adults aged 18 and older with sepsis, categorizing them based on the presence or absence of cardiac involvement, which will be assessed through clinical symptoms, biomarkers, ECG, and echocardiographic findings. The study will evaluate the persistence of cardiac abnormalities, functional capacity, and survival over one year, utilizing structured data collection and advanced statistical methods, including survival analysis and regression techniques, to identify predictors of adverse outcomes.

NCT Number	NCT07079605
Lead Sponsor	Jimma University Collaborators: Ethiopian Society of Cardiac Professionals
Conditions	Sepsis-related Myocarditis
Enrollment	226 participants
Start Date	2025-05-09
Primary Completion	2026-05-08 (estimated)
Study Completion	2026-09-22 (estimated)
Updated on ClinicalTrials.gov	2025-07-23