Micellar Water and the Skin Barrier: Comparing Rinsing vs. Non-Rinsing Application

The goal of this clinical trial is to assess how micellar water affects the skin barrier in healthy adult volunteers. The main questions it aims to answer are: * Does leaving micellar water on the skin affect skin barrier function differently than rinsing it off? * Are there measurable differences in transepidermal water loss (TEWL), skin hydration, and erythema between the two application methods? Researchers will compare the effects of micellar water left on the skin versus rinsed off after application. Participants will: * Be randomly assigned to one of two groups * Apply micellar water to their forehead once daily for 21 days * Either leave the micellar water on or rinse it off, depending on their group * Undergo non-invasive measurements of TEWL, skin hydration, and erythema before and after the intervention

NCT Number	NCT07079371
Lead Sponsor	University of Split, School of Medicine
Conditions	Effects of Micellar Water Application on Skin Barrier Integrity, Hydration, and Erythema in Healthy Skin
Enrollment	30 participants
Start Date	2025-06-18
Primary Completion	2026-01-01 (estimated)
Study Completion	2026-01-01 (estimated)
Updated on ClinicalTrials.gov	2025-07-23