Clinical Trial

Safety and Performance, and Dose, of OsteoAdapt DE in Localized Alveolar Ridge Augmentations

Study acronym: RESTORE
Active, Not Recruiting Phase 1/2
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Summary
This study's objective is to evaluate OsteoAdapt DE's safety and performance in comparison to Xenograft particulate bone graft for alveolar ridge augmentation. Additionally, the study aims to optimize OsteoAdapt DE dosing for future studies by assessing two concentrations: a low dose (0.8 mg/cc) and a high dose (2.0 mg/cc).
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-04-07
Trial Details
NCT Number NCT07078331
Lead Sponsor Theradaptive, Inc
Conditions Tooth Extraction Site Healing, Ridge Augmentation, Bone Graft
Enrollment 45 participants
Start Date 2025-07-17
Primary Completion 2026-04-01 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-06