Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center Study

OCT-A and eco-colordoppler are technologies which enable optic nerve head (ONH) blood perfusion detection. The aim of the study is to assess ONH vascular and structural components in optic neuropathies with and without ONH edema or pseudo-edema with OCT-A, and analyze ONH blood-flow with eco-colordoppler.

NCT Number	NCT07075887
Lead Sponsor	Barboni Collaborators: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, ASST Fatebenefratelli Sacco
Conditions	Neuro-Ophthalmology, Optic Neuropathies, Optic Atrophy, Hereditary, Leber, Optic Neuropathy, Anterior Ischemic, Optic Disc Drusen, Normal Tension Glaucoma (NTG)
Enrollment	70 participants
Start Date	2025-10
Primary Completion	2027-10 (estimated)
Study Completion	2028-10 (estimated)
Updated on ClinicalTrials.gov	2025-07-20