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The Synergism and Attenuation Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia

StatusNot Yet Recruiting
PhaseNot applicable
Started
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Record status
This record was last updated July 20, 2025 (before its estimated December 31, 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing self-harm. Carbamazepine (CBZ) is the first-line medication for TN, yet it presents adverse effects such as addiction and the absence of analgesic effects upon cessation. Acupuncture, particularly electroacupuncture（EA）, has demonstrated efficacy in TN treatment, although its therapeutic outcomes are influenced by various factors. This multicenter, randomized controlled trial aims to evaluate the synergistic efficacy-enhancing and toxicity-reducing effects of the optimized protocol when combined with carbamazepine (CBZ) in treating trigeminal neuralgia (TN), thereby proposing novel therapeutic refinements for electroacupuncture treatment regimens in TN management.
Trial Details
NCT Number NCT07074561
Lead Sponsor Yuanyuan Wu
Collaborators: Jiaxing Hospital of Traditional Chinese Medicine, Pingyang County Traditional Chinese Medicine Hospital
Conditions
(from sponsor)		 Trigeminal Neuralgia
Related terms Trigeminal Neuralgia
Enrollment 28 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov