Prospective Multiethnic Validation of the Behçet's Syndrome Overall Damage Index (BODI)

PROBE is an observational multicenter cohort study, consisting of a cross-sectional and a 5-years prospective phase, designed to target the major study objectives, such as testing the comprehensiveness of the Behçet's syndrome Overall Damage Index (BODI) in a wide and ethnically heterogeneous cohort of Behçet's syndrome patients, and investigating how damage assessed by the BODI correlates with other major long-term disease outcomes (5-years mortality and hospitalization rates).

NCT Number	NCT07073261
Lead Sponsor	University of Cagliari Collaborators: Hôpital de Hautepierre, University of Siena, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain., Università degli Studi di Ferrara, Tabriz University of Medical Sciences, University of Bari, Cairo University, Tehran University of Medical Sciences, Ibn Sina University Hospital, Rabat, Morocco, Istanbul University, Nazarbayev University School of Medicine, Aristotle University Of Thessaloniki, Mayo Clinic, Centro Hospitalar do Porto, Centro Hospitalar do Tâmega e Sousa, Federal University of São Paulo
Conditions	Behçet's Syndrome (BS)
Enrollment	970 participants
Start Date	2021-07-23
Primary Completion	2027-12-30 (estimated)
Study Completion	2027-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-07-18