Clinical Trial

Clinical Trial to Evaluate Safety, Tolerability, and Pharmacokinetics of SOF-SKN in Healthy Participants

Study acronym: HERACLES
Recruiting Early Phase 1
View on ClinicalTrials.gov →
Record status
This record was last updated July 20, 2025 (before its estimated February 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this study is to investigate the safety and tolerability of the topical application of SOF-SKN in healthy volunteers. The study will be divided into part 1 and part 2. Part 1, is a single ascending dose (SAD) design, while Part 2 is a multiple ascending dose (MAD) design.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-07-09.
Status change: Not Yet Recruiting → Recruiting 2025-07-17
Trial Details
NCT Number NCT07072611
Lead Sponsor Noxopharm Limited
Conditions Cutaneous Lupus Erythematosus
Enrollment 32 participants
Start Date 2025-07-14
Primary Completion 2026-02 (estimated)
Study Completion 2026-03 (estimated)
Updated on ClinicalTrials.gov 2025-07-20