Effects of Thumb Manipulation on Hand Grip Strength, Function, and Sensation

This randomized controlled study will aim to investigate the effects of thumb manipulation on hand grip strength, function, and sensation in healthy individuals. A total of 60 volunteers aged between 18 and 50 years will be recruited from Ortadağ Special Education and Rehabilitation Center. Participants will be randomly assigned to either a chiropractic manipulation group (n=30) or a control group (n=30), with an equal distribution of males and females in each group. The intervention group will receive thumb manipulation twice weekly for 4 weeks, while the control group will not receive any intervention. Outcome measures will include two-point discrimination (assessed with a discriminator), hand grip strength (measured using a dynamometer), pinch strength (evaluated with a pinch meter), and hand function (measured by the Duruöz Hand Index). Statistical analyses will be performed with a significance level set at p\<0.05. It is expected that participants in the manipulation group will show greater improvements in all measured parameters compared to the control group, suggesting a positive effect of thumb manipulation on hand-related sensorimotor functions in healthy individuals.

NCT Number	NCT07068698
Lead Sponsor	SEFA HAKTAN HATIK
Conditions	Thumb Manipulation, Hand Grip Strength, Hand Sensory Function, Hand Function in Healthy Individuals, Sensory Function
Enrollment	60 participants
Start Date	2025-07-06
Primary Completion	2025-08-06 (estimated)
Study Completion	2025-09-06 (estimated)
Updated on ClinicalTrials.gov	2025-07-16