Impact of Biphasic Cuirass Ventilation Compared to Non Invasive Ventilation in High Risk Extubations

subjects on mechanical ventilator who are about to be extubated to Non invasive ventilation because the physician thinks they are high risk for failure will be approached and consented for our study. Once randomized they will either be on the standard of care Non invasive arm or the intervention arm which would mean they are placed on the Biphasic cuirass ventilation.

NCT Number	NCT07067502
Lead Sponsor	University of Missouri-Columbia Collaborators: Hayek Medical
Conditions	Respiratory Failure, Extubation Failure
Enrollment	50 participants
Start Date	2026-10-01
Primary Completion	2027-03-30 (estimated)
Study Completion	2027-07-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-28