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Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices

Study acronym: Allena-mente
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated July 15, 2025 (before its estimated May 5, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Minor Study First Submitted
3,531 trials monitored
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1,978 trials monitored
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and 2 more diseases
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases. This study aims to evaluate the effectiveness of traditional physical activities combined with innovative interventions such as cryotherapy, ultrasound therapy, laser therapy, transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS). It will also assess the impact of proprioceptive stimuli provided by either the immersive virtual reality (CAREN), or visuo-cognitive-motor enhancement (S.V.T.A.), and music therapy. The main questions it aims to answer are: How do these interventions affect motor activities and their functional recovery? What are the temporal and spatial changes in activation sequences related to motor learning and maintenance? When there is a comparison group: Researchers will compare outcomes between different intervention arms (e.g., physical activity with advanced devices vs. traditional methods) to find out if the advanced interventions result in better motor control and functional recovery. Participants will: * Undergo various rehabilitation protocols including physical activity and advanced interventions. * Be assessed using different tool, such as fMRI, dtMRI, and NIRS to study in vivo neuroimaging and assess changes in brain function and connectivity.
Trial Details
NCT Number NCT07066137
Lead Sponsor IRCCS Centro Neurolesi Bonino Pulejo
Conditions
(from sponsor)
Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease, Dementia, Stroke
Related terms Alzheimer Disease, Dementia, Multiple Sclerosis, Parkinson Disease, Stroke
Enrollment 150 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov