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Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis

StatusActive, Not Recruiting
PhasePhase 2
Started2025-05-05
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 4, 2026 (before its estimated September 2026 completion). Its status may not reflect the trial's current state.

Amendment history

2026-02-03
Recruiting→Active, Not Recruiting Study Status, Contacts/Locations v2
Trial statusRecruiting→Active, Not Recruiting
Primary completion date2026-03→2026-09
Completion date2026-05→2026-09
Study sitesdetails revised at 5 of 5 sites
2025-09-15
Study Status, Contacts/Locations v1
Study sites3→5
2025-07-10
Original filing
This is a multicenter, open label study designed to evaluate the safety, tolerability, and efficacy of topically administered VTR-297 solution. The efficacy objectives of the study will be assessed using fungal culture testing, Neutral Red Staining (NRS) microscopy examination, and KOH microscopy examination after 4 weeks of treatment with VTR-297.
Trial Details
NCT Number NCT07065773
Lead Sponsor Vanda Pharmaceuticals
Conditions Onychomycosis of Toenail
Enrollment 50 participants
Start Date 2025-05-05
Primary Completion 2026-09 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-02-04