Tubeless VATS for Mediastinal Neoplasm

In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm remain controversial. This randomized controlled trial is designed to evaluate the impact of the non-intubated approach on surgical and perioperative outcomes in patients undergoing mediastinal neoplasm resection.

NCT Number	NCT07065604
Lead Sponsor	Shuben Li Collaborators: The First Affiliated Hospital of Guangzhou Medical University
Conditions	Mediastinal Neoplasm, VATS, Tubeless, Non-intubated Anesthesia
Enrollment	132 participants
Start Date	2025-03-26
Primary Completion	2028-05-01 (estimated)
Study Completion	2028-08-31 (estimated)
Updated on ClinicalTrials.gov	2025-07-15