Predictive Model for PENS Response in Subacromial Pain Syndrome

Subacromial pain syndrome (SPS) is one of the most common causes of shoulder pain, leading to significant disability and socioeconomic burden. Although percutaneous electrical nerve stimulation (PENS) targeting the suprascapular nerve (SN) has shown positive therapeutic outcomes, individual response to the intervention varies considerably. This study aims to develop a multivariable predictive model to estimate clinical response to SN-targeted PENS in patients with SPS. The model will be built using clinical, psychological, and neural mechanosensitivity variables. The goal is to enhance patient selection and guide personalized treatment strategies.

NCT Number	NCT07063641
Lead Sponsor	Néstor Requejo Salinas Collaborators: University of Alcala, Centro Universitario La Salle
Conditions	Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain
Enrollment	269 participants
Start Date	2025-09-20
Primary Completion	2026-11-10 (estimated)
Study Completion	2026-11-10 (estimated)
Updated on ClinicalTrials.gov	2025-07-14