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Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE）

Name: Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE） — clinical trial record (NCT07063108)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusNot Yet Recruiting

PhasePhase 4

SponsorChinese PLA General Hospital

Started2025-12-01

View on ClinicalTrials.gov ↗

Record status

This record was last updated July 14, 2025 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Chinese PLA General Hospital

193 trials monitored

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This national, multi-center, randomized controlled study, through the study of intravenous injection of estaketamine in elderly patients undergoing surgery, is expected to explore whether estaketamine can improve the acute postoperative pain of elderly patients undergoing surgery and reduce the incidence of postoperative depression and delirium.

Trial Details

NCT Number	NCT07063108
Lead Sponsor	Chinese PLA General Hospital
Conditions	Postoperative Pain
Enrollment	276 participants
Start Date	2025-12-01
Primary Completion	2026-06-30 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-07-14