Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy

This study will be conducted to evaluate the effects of different anesthetic modalities \[sevoflurane with or without intraoperative lidocaine infusion and Propofol total intravenous anesthesia (TIVA)\] on intracranial pressure (ICP) and cerebral oxygenation assessed by non-invasive methods during laparoscopic hysterectomy (LH).

NCT Number	NCT07062367
Lead Sponsor	Tanta University
Conditions	Sevoflurane, Lidocaine, Propofol, Intracranial Pressure, Cerebral Oxygenation, Laparoscopic Hysterectomy
Enrollment	90 participants
Start Date	2025-02-01
Primary Completion	2027-02-01 (estimated)
Study Completion	2027-02-01 (estimated)
Updated on ClinicalTrials.gov	2025-07-14