Clinical Trial

Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I)

Suspended Phase 2
View on ClinicalTrials.gov →
Why the trial stopped
Suspended due to lack of drug supply: the manufacturer ceased to provide investigational drug supply.
Summary
The purpose of this study is to explore the efficacy and safety of involved-field radiotherapy-TNT combined with PD-1 inhibitors in pMMR locally advanced rectal cancer.
Protocol Amendment History 2 changes
critical Recruitment suspended 2026-08-01
critical Recruitment suspended: Suspended due to lack of drug supply: the manufacturer ceased to provide investigational drug supply. 2026-08-01
Trial Details
NCT Number NCT07057089
Lead Sponsor Hebei Medical University Fourth Hospital
Conditions Locally Advanced Rectal Cancer
Enrollment 90 participants
Start Date 2025-07-01
Primary Completion 2028-03-01 (estimated)
Study Completion 2030-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-31