Applying Population Management Best Practices to Preventative Genomic Medicine Trial

Preventive genomic medicine, particularly identification of individuals with inherited cancer risk, can improve longevity and quality of life, yet adherence to risk management following cancer genomic testing is poor. The proposed research refines and evaluates two highly scalable population management interventions, web resources and personalized outreach, designed to improve access and use of recommended risk management following cancer genetic testing. Research activities will be conducted in a vertically integrated health system and federally qualified health center and will address post-testing quality and patient safety concerns that are minimizing patient benefit and slowing investments in real world genomic medicine implementation.

NCT Number	NCT07053813
Lead Sponsor	University of Washington Collaborators: National Human Genome Research Institute (NHGRI)
Conditions	Neoplastic Syndromes, Hereditary
Enrollment	900 participants
Start Date	2025-07-01
Primary Completion	2027-07-01 (estimated)
Study Completion	2028-07-01 (estimated)
Updated on ClinicalTrials.gov	2026-02-27