The Characteristics and Treatment Mechanism of Vascular Grafts in Elderly Patients With CAOD Through Single-cell Transcriptome Analysis

This study aims to establish a cardiovascular biobank using vascular grafts obtained from participants with coronary artery occlusive disease (CAOD). Through genomic and transcriptomic analyses, the study seeks to characterize the biological features of the vascular grafts and identify potential therapeutic targets and mechanisms related to vascular remodeling and stiffness.

NCT Number	NCT07053254
Lead Sponsor	Yonsei University
Conditions	Coronary Artery Occlusive Disease (CAOD)
Enrollment	100 participants
Start Date	2022-04-12
Primary Completion	2027-04-11 (estimated)
Study Completion	2027-04-11 (estimated)
Updated on ClinicalTrials.gov	2025-07-08