Clinical Trial

Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

Study acronym: FOCUS
Recruiting
View on ClinicalTrials.gov →
Summary
The investigators hypothesize that pregnancy and preconception care may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal or preconception/fertility care. The goal is to evaluate the acceptability of BRCA1/2 testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention and be cost-effective, especially among underserved populations.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2025-06-26; most recent amendment 2025-12-18.
Status change: Not Yet Recruiting → Recruiting 2025-10-27
Trial Details
NCT Number NCT07052266
Lead Sponsor Weill Medical College of Cornell University
Collaborators: Myriad Genetics, Inc.
Conditions Hereditary Cancer Syndromes
Enrollment 550 participants
Start Date 2025-09-02
Primary Completion 2027-06 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2025-12-26