Prospective Cohort and Biobank of Patients With Nonalcoholic Fatty Liver Disease

The goal of this observational study is to establish a unified cohort for retrospective and prospective high quality baseline and follow-up data registration of patients with a diagnosis of NAFLD/NASH/MAFLD, according to standardized criteria. This will allow future studies aimed at elucidate clinical presentation, natural history, response to treatment, genetic and metabolic risk factors, treatment options and outcomes of the disease. The cohort will allow investigators to carry out genetic, serological, microbiologic and immunological studies.

NCT Number	NCT07051863
Lead Sponsor	Fondazione Epatocentro Ticino
Conditions	NAFLD, MASH, NASH/MASH
Enrollment	300 participants
Start Date	2023-07-19
Primary Completion	2030-12 (estimated)
Study Completion	2030-12 (estimated)
Updated on ClinicalTrials.gov	2026-07-21