Clinical Trial

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

Study acronym: AIRFLOW-4
Recruiting
View on ClinicalTrials.gov →
Summary
The dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care. The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System in the treatment of COPD.
Protocol Amendment History 1 change
notable Trial sites expanded: 6 -> 10 locations 2026-04-29
Trial Details
NCT Number NCT07051707
Lead Sponsor Nuvaira, Inc.
Collaborators: Temple Health
Conditions COPD, Chronic Obstructive Pulmonary Disease
Enrollment 200 participants
Start Date 2026-02-24
Primary Completion 2028-04-30 (estimated)
Study Completion 2029-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-28