Laser Posterior Nasal Nerve Neurolysis

This clinical trial aims to learn if laser posterior nasal nerve neurolysis can treat chronic rhinitis in adults. It will also learn about the safety of laser posterior nasal nerve neurolysis. The main questions it aims to answer are: 1. Does laser posterior nasal nerve neurolysis improve chronic rhinitis symptoms? 2. What side-effects or complications do participants have after laser posterior nasal nerve neurolysis? Researchers will compare laser posterior nasal nerve neurolysis to a placebo(a sham surgery with the same device and sound to see if laser posterior nasal nerve neurolysis works to treat chronic rhinitis. Participants will 1. Receive laser posterior nasal nerve neurolysis in the office as local anesthesia surgery. 2. Visit the clinic in the first week, first month, and 3rd months after the surgery. 3. Record their symptom scores before the surgery and during each follow-up visit.

NCT Number	NCT07050992
Lead Sponsor	Chiayi Christian Hospital
Conditions	Allergic Rhinitis, Chronic Rhinitis, Rhinorrhea, Sneezing, Nasal Obstruction, Nasal Congestion, Nasal Allergies, Nasal Stuffiness
Enrollment	120 participants
Start Date	2024-11-01
Primary Completion	2025-12-06 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2025-12-17