Clinical Trial

Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation

Terminated Early Phase 1
View on ClinicalTrials.gov →
Why the trial stopped
Per Principal Investigator decision.
Summary
This study plans to learn more about using contrast enhanced ultrasound (CEUS) in brain tumor surgery. The goal of glioma brain tumor surgery is to remove as much of the glioma as possible. Tumor tissue that is close to normal brain tissue can look very similar. This can make it difficult for the surgeon to remove all the tumor. In this study, we hope to learn if using CEUS during brain tumor surgery will allow the brain surgeon to better see and remove all the tumor tissue.
Protocol Amendment History 4 changes
critical Trial terminated 2026-06-23
notable Enrollment reduced: 100 -> 2 participants 2026-06-23
notable Primary completion moved earlier: 2026-12-31 -> 2026-01-16 2026-06-23
minor Completion moved earlier: 2027-06 -> 2026-01-27 2026-06-23
Trial Details
NCT Number NCT07050836
Lead Sponsor University of Colorado, Denver
Conditions Glioma (Any Grade) in the Brain, Glioma
Enrollment 2 participants
Start Date 2025-12-05
Primary Completion 2026-01-16 (estimated)
Study Completion 2026-01-27 (estimated)
Updated on ClinicalTrials.gov 2026-06-22