Hypoglossal Nerve Stimulation for the Treatment of Adult Obstructive Sleep Apnea

The goal of this interventional study is to assess the safety and performance of the XII Medical Hypoglossal Nerve Stimulation (HGNS) System in people who have moderate to severe Obstructive Sleep Apnea (OSA). Participation in this study involves being implanted with a Neurostimulator which provides electrical stimulation of the hypoglossal nerve (HGN). Participants will receive treatment at home during sleep, and participate in sleep studies to track and record the quality of the sleep. Participants will be monitored over the course of the study.

NCT Number	NCT07049744
Lead Sponsor	XII Medical
Conditions	Obstructive Sleep Apnea (OSA)
Enrollment	30 participants
Start Date	2025-06-24
Primary Completion	2026-12 (estimated)
Study Completion	2029-06 (estimated)
Updated on ClinicalTrials.gov	2026-07-30