Clinical Trial

Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy

Study acronym: NOTICE-1
Recruiting
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Summary
1. The goal of this clinical trial is to evaluate the efficacy and safety of hyperbaric oxygen (HBO)in stroke patients after endovascular treatment 2. The main questions it aims to answer is: Whether HBO can improve the prognosis of ischemic stroke patients after endovascular treatment? 3. Participants will: receive HBO (1.6 Atmosphere Absolute,1.6ATA),Once a day, for 1 hour each time, for 5 days a week (it can be non-consecutive days), the total course of treatment is 10 times. undergo three scheduled face to face or telephone follow-up assessments during the 12-month period following HBO.
Protocol Amendment History 1 change
critical Recruitment opened 2026-07-25
Trial Details
NCT Number NCT07049692
Lead Sponsor Beijing Chao Yang Hospital
Conditions Acute Ischemic Stroke
Enrollment 424 participants
Start Date 2026-07-22
Primary Completion 2028-03-30 (estimated)
Study Completion 2028-03-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-24