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Perioperative Intravenous Nimodipine Trial

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 7 months later May 19, 2026 → Dec 19, 2026
See other at-risk trials from University of Ioannina

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion pushed from May 19, 2026 to Dec 19, 2026
    • Study description shortened, about 5 words
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The role of perioperative IV administration of nimodipine, an L-type calcium channel antagonist which is capable of crossing the blood-brain barrier, on peri-operative opioid and anesthetics requirements, pain intensity, opioid-related side effects and early postoperative bowel mobility in patients undergoing surgical treatment for bowel cancer with open radical colectomy remains scarcely explored. A prospective double-blind, randomized controlled trial investigating the effect of perioperative IV administration of nimodipine in patients undergoing open colectomy for cancer treatment is therefore conducted.
Trial Details
NCT Number NCT07048522
Lead Sponsor University of Ioannina
Conditions
(from sponsor)		 Colectomy, Open Surgery, Pain, Pain, Postoperative, Pain, Acute
Related terms Acute Pain, Pain, Postoperative Pain
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov