Tibial Nerve Elastography in Chemotherapy-Induced Neuropathic Pain

This observational study aims to evaluate the tibial nerve stiffness using Shear Wave Elastography (SWE) in patients with chemotherapy-induced peripheral neuropathy (CIPN) compared to healthy volunteers. A total of 25 patients with a DN4 score ≥4 and 25 healthy controls will be assessed. Parameters including nerve diameter, cross-sectional area, depth, and shear wave velocity (V value) will be measured. Demographic and clinical data such as age, gender, chemotherapy protocol, duration, comorbidities, and medications will also be collected. The goal is to investigate SWE as a non-invasive diagnostic tool for CIPN by identifying differences in nerve elasticity between groups.

NCT Number	NCT07048431
Lead Sponsor	Ankara Etlik City Hospital
Conditions	Chemotherapy-induced Peripheral Neuropathy, Tibial Neuropathy
Enrollment	50 participants
Start Date	2025-09-15
Primary Completion	2025-10-15 (estimated)
Study Completion	2025-11-15 (estimated)
Updated on ClinicalTrials.gov	2025-07-02