Personalization of External Beam Radiation Therapy in Localised Tumours

The study will include the prospective acquisition of optimized MR imaging data of prostate and breast patients treated with radiotherapy (RT). Within the prospective study, biological specimens from patients undergoing in-room biopsy before RT, will be collected. Histological evaluation and cell culture (and organoid preparation) will be conducted, and samples/organoids will be irradiated with RT for biological validation.

NCT Number	NCT07047495
Lead Sponsor	European Institute of Oncology
Conditions	Breast Adenocarcinoma, Prostate Cancer (Adenocarcinoma)
Enrollment	35 participants
Start Date	2025-07
Primary Completion	2030-07 (estimated)
Study Completion	2030-07 (estimated)
Updated on ClinicalTrials.gov	2025-07-02