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Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

Study acronym: PLP Home-Based
StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated August 8, 2025 (before its estimated May 31, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary completion date: Mar 31, 2026 to May 31, 2026
    • Study completion date: Aug 31, 2026 to May 31, 2026
    • Publications: details revised at 8 of 8 entries
    v4
  2. Primary completion date: Aug 30, 2025 to Mar 31, 2026
    • Study completion date: Aug 30, 2025 to Aug 31, 2026
    • Study description shortened, about 9 words
    v3
  3. Primary endpoints revised (2)
    • Interventions: Actiive Virtual Reality Treatment (Behavioral) to Active Virtual Reality Treatment (Behavioral)
    • Publications: details revised at 8 of 8 entries
    v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The study will explore the feasibility and efficacy of a home-based, active VR treatment for phantom limb pain (PLP).
Trial Details
NCT Number NCT07044323
Lead Sponsor Albert Einstein Healthcare Network
Collaborators: University of Pennsylvania
Conditions
(from sponsor)		 Phantom Pain Following Amputation of Lower Limb, Amputation
Related terms Pain, Phantom Limb
Enrollment 44 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov