Clinical Trial

Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

Study acronym: PLP Home-Based
Recruiting
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Record status
This record was last updated August 8, 2025 (before its estimated May 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The study will explore the feasibility and efficacy of a home-based, active VR treatment for phantom limb pain (PLP).
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-06-23; most recent amendment 2025-08-07.
Trial Details
NCT Number NCT07044323
Lead Sponsor Albert Einstein Healthcare Network
Collaborators: University of Pennsylvania
Conditions Phantom Pain Following Amputation of Lower Limb, Amputation
Enrollment 44 participants
Start Date 2025-06-16
Primary Completion 2026-05-31 (estimated)
Study Completion 2026-05-31 (estimated)
Updated on ClinicalTrials.gov 2025-08-08