The Influence of Virtual Reality on Blood Parameters

The goal of this study is to learn what the impact of exposure to virtual reality content is on the levels of stress-related blood values in healthy volunteers. The main question it aims to answer is: * To compare the levels of stress-related biomarkers before and after relaxing VR-content (Relax Visit); * To compare the levels of stress-related biomarkers before and after stress-inducing VR-content (Rollercoaster Visit). Researchers will compare the Relax and Rollercoaster Visit to see if there is a relationship between the relaxing and stress-inducing VR content on stress-related blood values. Participants will be asked to watch relaxing or stress-inducing VR content for approximately five minutes. Blood will be withdrawn before and after intervention. After 3-5 weeks the study visit will be repeated using the other VR content.

NCT Number	NCT07042178
Lead Sponsor	Van Creveldkliniek
Conditions	Virtual Reality Pain Distraction, Endocrinology, Haematology
Enrollment	30 participants
Start Date	2025-08-27
Primary Completion	2026-02-20 (estimated)
Study Completion	2026-02-20 (estimated)
Updated on ClinicalTrials.gov	2026-04-29