Clinical Trial

Treatment of Bile Acid Diarrhoea With Atorvastatin

Study acronym: BASTA
Active, Not Recruiting Phase 4
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Summary
Bile acid diarrhoea (BAD) is a socially debilitating disease with stomach pain, high stool frequency, urgency, and faecal incontinence as the main symptoms. Studies estimate that 1-2% of the population suffers from the disease. There is an unmet need for more treatment options in patients suffering from BAD. The investigators hypothesise that atorvastatin treatment lowers bile acid synthesis in patients with bile acid diarrhoea. The investigators will investigate this hypothesis in the current study, BASTA, which is a Randomised, Double-Blind, Placebo-Controlled, Crossover, Proof of Concept, Investigator-Initiated, Trial.
Protocol Amendment History 1 change
critical Enrollment closed, study ongoing 2026-08-12
Trial Details
NCT Number NCT07042165
Lead Sponsor Asger Lund, MD
Collaborators: Fonden til Lægevidenskabens Fremme, Prosektor Axel Søeborg Ohlsens Mindelegat, Læge Sofus Carl Emil Friis og Hustru Olga Doris Friis' Legat, Aase and Ejnar Danielsens Foundation
Conditions Bile Acid Diarrhea, Bile Acid Malabsorption
Enrollment 20 participants
Start Date 2025-10-15
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-11