Clinical Trial

Cognitive Stimulation in Older Adults With Alzheimer's Disease

Completed
View on ClinicalTrials.gov →
Summary
This multicentre study, employing a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions that provide care and support services for older adults diagnosed with mild to moderate Alzheimer's disease (AD). The primary aim is to evaluate the effects of two distinct cognitive stimulation modalities (digital vs physical/analogue). The study will assess the impact of individual cognitive stimulation on multiple domains - specifically cognitive function (with an emphasis on memory and executive function), mood, and quality of life - and investigate how institutional and territorial characteristics influence these effects, considering geographical and organisational diversity as potential moderating factors.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2025-06-24; most recent amendment 2026-03-23.
Status change: Active, Not Recruiting → Completed 2026-03-23
Status change: Recruiting → Active, Not Recruiting 2026-02-11
Status change: Not Yet Recruiting → Recruiting 2025-09-05
Trial Details
NCT Number NCT07041008
Lead Sponsor Rsocialform - Geriatria, Lda
Conditions Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction, Cognitive Decline
Enrollment 514 participants
Start Date 2025-09-01
Primary Completion 2025-09-13 (estimated)
Study Completion 2026-03-13 (estimated)
Updated on ClinicalTrials.gov 2026-03-25